This volume presents the results of the archaeological investigations in the oasis of Fewet (SW Libyan Sahara), carried out by the Archaeological Mission in the Sahara of the Sapienza University of Rome. Evidences of an ancient rural village were identified under the houses of the modern town of Tan Afella and a large necropolis, dated to the Garamantian times, spread at the fringes of the modern settlement. Until 1997 very little was known on the Garamantian period in the Wadi Tanezzuft area and on the transition from the pastoral to the early-historical phase. This period witnessed the gradual sedentarisation of human groups in the oases, and the development of caravan routes with the flourishing of an intra- and trans-Saharan trade. These processes, also influenced by significant alterations in climate, which led to the agricultural exploitation of the limited areas where water resources were available – the oases – were archaeologically unknown as far as settlements were concerned. The archaeological surveys and excavations carried out in the area of Fewet were particularly promising and are here analysed in a multidisciplinary perspective, which takes into consideration environmental and anthropological studies in the attempt to reconstruct the culture and the life of people inhabiting the Southern Fezzan region in early-historical times.