This book introduces an innovative methodological approach to interpreting Venice’s cultural heritage through a detailed examination of material culture. It delves into the phenomenon of the reuse of ancient stone and marble in Venice and its surrounding areas, spanning from Antiquity to the Baroque period. The volume focuses on the identification and interpretation of lithic materials reused in both private and religious structures, including the iconic Basilica of St. Mark, where they are applied as interior or exterior cladding or used as decorative sculpture.